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Company Database


about this company


1-6-1 Okubo, Kita-ku, Kumamoto, 860-8568, Japan

Phone Number:


Fax Number:


Company Contact Email:



2,029 (June 2023)


USD 71.4M [Total USD 7.6B for the Meiji group companies] (1USD=140JPY)


USD 306M [Total USD 7.6B for the Meiji group companies] (1USD=140JPY)

Main Clients:

Meiji Seika Pharma

Introduction of your company & business:

KM Biologics supplies first-rate biological products and services with sophisticated skills and knowledge based on over 70 years of combined experience. Our main businesses include the following:

Human Vaccines

Blood Plasma Products

Veterinary Vaccines

Newborn Screening


Our responsibility as disease prevention and treatment professionals is to continuously push the limits of life sciences to shape a healthy future for people around the world.


1945: Establishment of our predecessor, Kaketsuken

1946: Vaccine production for smallpox and cholera, a combined vaccine against typhus and paratyphoid, and a tetanus antitoxin started.

1964: Approval of DPT vaccine.

1988: Launch of Bimmugen – the first Japanese recombinant Hepatitis B vaccine.

1991: Launch of Bolheal – the first Japanese fibrin sealant

2001: Succeeded in full-length cDNA cloning of ADAMTS13

2014: Launch of a new haemostatic treatment for haemophillia patients with inhibitors: Byclot – human coagulation factor VIIa containing factor X

2018: Kaketsuken joined Meiji Group and renamed to KM Biologics.

2023: Approval of Quintovac, a pentavalent vaccine for use in Japan.

Key Products or Services:

Seasonal and pandemic influenza vaccines, Pentavalent vaccine, Japanese encephalitis vaccine, Human coagulation factors, Newborn Screening

Factory Equipment:

Dedicated facilities and equipment for manufacturing various types of vaccines and plasma derived therapies regularly inspected and approved by the Japanese authorities (PMDA).

Technology / R&D activities:

With a commitment to discovery, innovation, and excellence, our scientists carry out cutting-edge research that helps contribute to a healthy future for people around the world.

Inactivated COVID-19 vaccine

Live attenuated tetravalent dengue vaccine

Hexavalent vaccine

Recombinant vaccines

International Operations:

So far KM Biologics has supplied vaccines only in Japan. We are looking for strategic partners to explore the overseas markets.

Business Achievements:

After the 2009 pandemic influenza outbreak, we were the first in the world to establish a domestic vaccine supply system – and today we boast the capability to supply the vaccine to around 57 million people


KM Biologics has been included in the list of “Certified Health & Productivity Management Outstanding Organizations Recognition Program” by the Ministry of Economy, Trade and Industry three consecutive years, as a company that has an excellent health and productivity management system in place.

Company Goals & Objectives:

Overseas expansion of registered products and testing systems.

Further broadening of our product portfolio with a focus on immunologic, hematologic and congenital disease area.

Becoming a strategic development, manufacturing and sales partner mainly in Japan and APAC region.

Developing new generation of pharmaceuticals by adoption of new modalities